Alexandra Shin Image

Alexandra Shin, Ph.D.

Associate Professor of Biology

Office Phone: (951) 552 - 8453
Office Location: Mission Hall 103
Office Hours: Monday 10:30am - 12:00pm; Wednesday 10:30am - 2:30pm; Friday 10:30am - 1:00pm

Degree Major Emphasis Institution Year
Ph.D. Pharmacology Loma Linda University 2015
B.S. Biology George Fox University 2011
  • Courses Taught

    Pharmacology with Discussion (BIO440)
    General Biology II with Lab (BIO148, BIO148L)
    Anatomy & Physiology I with Lab (BIO153)
    Anatomy & Physiology II with Lab (BIO163)
    Topics in Health Coaching (BIO412B)
    Principles of Biology and Lab (BIO143, BIO143L)
    Science, Technology, and Worldview (WLD121)

    Graduate Courses:
    Medical Pharmacology for M.S. in Biomedical Sciences (BIO535)
    Anatomy and Physiology I and II for Physician Assistants (PAS501, PAS502)
    Advanced Pharmacology for Master's in Nursing (NUR558)

  • Academic Areas & Scholarly Interests

    Developmental Origins of Health and Disease
    Cardiovascular system
    Heart Disease
    Perinatal Biology
    Pediatric neurodegeneration
    Pediatric neuroinflammation
    Disease prevention
    Lifestyle medicine
    Community health

  • Research, Presentations, & Publications

    Shin SDK, Shin A, Mayagoitia K, Siebold L, Rubini M, Wilson CG, Bellinger D, Soriano S. (2019) "Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C," Neuroinflammation.

    Shin SD, Shin A, Mayagoitia K, Wilson CG, Bellinger DL, Soriano S. (2019) Interferon downstream signaling is activated early in pre-symptomatic Niemann-Pick disease type C. Neuroscience Letters.

    Shin AN, Han L, Dasgupta C, Huang L, Yang S, Zhang L. (2018) SIRT1 increases cardiomyocyte binucleation in the heart development. Oncotarget.

    Shin AN, Dasgupta C, Zhang G, Seal K, Zhang L. (2016) Proteomic analysis of endothelin-1 targets in the regulation of cardiomyocyte proliferation. Current Topics in Medicinal Chemistry.

    Paradis AN, Gay M, Wilson C, Zhang L. (2015) Newborn hypoxia/anoxia inhibits cardiomyocyte proliferation and decreases cardiomyocyte endowment in the developing heart: role of endothelin-1. PLoS One.

    Song M, Paradis A, Gay M, Shin J, Zhang L. (2014) Differential expression of microRNAs in ischemic heart disease. Drug Discovery Today.

    Paradis A, Xiao D, Zhou J, Zhang L. (2014) Endothelin-1 promotes cardiomyocyte terminal differentiation in the developing heart via heightened DNA methylation. International Journal of Medical Sciences.

    Paradis AN, Gay MS, Zhang L. (2013) Binucleation of cardiomyocytes: the transition from a proliferative to a terminally differentiated state. Drug Discovery Today.

    Paradis A, Zhang L. (2013) Role of endothelin in uteroplacental circulation and fetal vascular function. Current Vascular Pharmacology.

    Zhou J, Xiao D, Hu Y, Wang Z, Paradis A, Mata-Greenwood E, Zhang L. (2013) Gestational hypoxia induces preeclampsia-like symptoms via heightened endothelin-1 signaling in pregnant rats. Hypertension.

  • Church Membership & Activities

    Crosswalk Church

  • Interests & Hobbies

    I am very invested in personal and community health, especially in preventing chronic diseases related to lifestyle choices. I am also passionate about my research that looks at long-term health related to in utero stresses (smoking, alcohol, hypoxia, diet, etc.). Recently, I have also found a new interest in pediatric neurological diseases. In my spare time, I enjoy hiking and backpacking with my husband.