Dennis K. Bideshi, Ph.D.

1985-1986
Huntington Memorial Hospital
Department of Laboratory Medicine
School of Medical Technology
Clinical Microbiology
Pasadena, California

BIO533: Infection and Immunity
BIO489: Immunity and Molecular Pathogenesis
BIO 412: Current Topics in Biology
BIO 435/L: Proteomics, Genomics, and Bioinformatics with Laboratory
* BIO 399: Independent Research
* BIO 334/L: Vertebrate Physiology with Laboratory
* BIO 330/L: Cell and Molecular Biology with Laboratory
* BIO 313: Genetics
* BIO 305/L: Microbiology with Laboratory
* BIO 205/L: Human Microbiology with Laboratory
* BIO 163/L: Anatomy and Physiology II with Laboratory
* BIO 153/L: Anatomy and Physiology I with Laboratory
* BIO 114/L: General Botany with Laboratory
* MSC120/L: Topics in Marine Science with Laboratory for Non-Science Majors
* MSC412/L: Topics in Marine Science with Laboratory for Science Majors
PAS505: Infectious Diseases/Clinical Microbiology
PAS526: Infectious Diseases/Clinical Microbiology
PAST547: Infectious Diseases/Clinical Microbiology

Research Interests:

My specific research interests are focused in three major areas: 1. understanding the molecular mechanisms responsible for replication, cytopathology, and biological diversity of large, circular double-stranded DNA, entomopathogenic viruses belonging in the family Ascoviridae and Baculoviridae; 2. understanding the genetic mechanisms responsible for the regulation of synthesis and crystallization of endotoxins in the entomopathogenic bacteria, including Bacillus thuringiensis subsp. israelensis and B. sphaericus, with an applied emphasis; and 3. understanding the genetic basis for transfer of large toxigenic plasmids among environmental strains of Bacillus thuringiensis, Bacillus cereus and Bacillus anthracis. Most of this work is done in collaboration with Dr. Brian A. Federici (University of California, Riverside, UCR), Dr. Hyun-Woo Park (CBU, UCR), Dr. Yves Bigot (UMR INRA-CNRS 7247, PRC, Centre INRA de Nouzilly, France), Dr. J. E. Barboza-Corona (University of Guanajuato, México), and Dr. Izabela Swiecicka (University of Bialystok, Poland).


1. Ascoviruses. The ascoviruses are intriguing for study in that they demonstrate a novel cytopathology in insect cells where they induce a modified form of genetically programmed cell-death (apoptosis) that is unique among all known viruses. Since our publication of the annotated genomic sequence of the type species, the Spodoptera frugiperda ascovirus 1a (SfAV1a), we have made significant progress in elucidating the novel ultrastructure of this virus and in elucidating a mechanism for its genomic DNA condensation and encapsidation. In addition, with our colleagues in France, we have made important strides in understanding the phylogenetic relationship of ascoviruses and iridoviruses. Our recent and current work continues in the area of understanding the molecular biology of ascovirus cytopathology, ultrastructure, and diversity.

2. Bacillus thuringiensis. With regard to the entomopathogenic bacteria, a better knowledge of the genetic mechanisms that regulate protein toxin synthesis and crystallization not only provides basic scientific insights into these processes, but also contributes to the development of novel biopesticides that target insect vectors of viral and parasitic diseases, such as the West Nile virus and malaria. The technology developed through our research in Dr. Federici’s laboratory has already yielded genetically engineered strains of bacteria with markedly improved mosquitocidal activities, several of which potentially have applied value. Our most recent work focuses on the intermolecular interactions between the cytolytic toxin (Cyt1Aa) and various crystal toxins (Cry) as a basis for understanding their synergy against mosquito and lepidopteran larvae, and for developing various novel combinations of Cyt1Aa and Cry toxins for applied use. My current work is to decipher the genetic determinants and mechanisms responsible for the synthesis of a multilamellar fibrous matrix that surrounds each of the crystalline inclusions and the mature parasporal body of B. thuringiensis subsp. israelensis. In this regard, our group has already identified at least two key protein required for the structure and stability of the parasporal body.

3. Toxigenic plasmid replication and transmission. We are in the process of deciphering the mechanism by which the large toxigenic plasmid, pBtoxis, in B. thuringiensis subsp. israelensis replicates. Here, we have identified the essential genes and cis-elements harbored in pBtoxis that are required for plasmid propagation and have shown that the mechanism is related to the system used by the toxigenic plasmid in B. anthracis. Indeed, a key component required for replicative function of these toxigenic plasmids is a novel FtsZ/tubulin-like protein, uncommon in the prokaryotic world. Our initial publications, and those in only a few reports by others, indicate that the toxigenic plasmids in Bacillus species have a replicative system unique among prokaryotes. This system was recently designated as the Type III plasmid segregation system. My current interest and future work in this area is to understand transmission of large toxigenic plasmid among natural Bacillus species.

1986-1993
Huntington Memorial Hospital
Department of Laboratory Medicine,
School of Laboratory Medicine,
Clinical Microbiology
2009

Loma Linda University
School of Pharmacy
Adjunct Professor: Infectious Diseases/Microbiology

2010-Present
Loma Linda University
Physician Assistant Sciences Program
Adjunct Professor: Infectious Diseases/Microbiology

2014-Present
Marshall B. Ketchum University
School of Physician Assistant Studies
Adjunct Professor: Infectious Diseases/Microbiology

A. CO-AUTHORED PEER-REVIEWED PUBLICATIONS

97. Martinez-Zavala, S.A., Ortiz-Rodriguez, T., Salcedo-Hernandez, R., Casados-Vazquez, L.E., Del Rincon-Castro C.M., Bideshi, D.K., Barboza-Corona, J.E. 2024. The chitin-binding domain of Bacillus thuringiensis ChiA74 inhibits Gram-negative bacterial and fungal pathogens of humans and plants. International Journal of Biological Macromolecules. International Journal of Biological Macromolecules 254 (2024):228049. https://doi.org/10.1016/j.ijbiomac.2023.128049

96. Lainey J. Williamson , Marina Galchenkova , Hannah L. Best , Richard J. Bean , Anna Munke, Salah Awel, Gisel Pena , Juraj Knoska, Robin Schubert, Katerina Dörner , Hyun-Woo Park, Dennis K. Bideshi, Alessandra Henkel, Viviane Kremling, Bjarne Klopprogge, Emyr Lloyd-Evans, Mark T. Young, Joana Valerio, Marco Kloos, Marcin Sikorsk, Grant Mills, Johan Bielecki, Henry Kirkwood, Chan Kim, Raphael de Wijn, Kristina Lorenzen, Paul Lourdu Xavier, Aida Rahmani Mashhour, Luca Gelisio, Oleksandr Yefanov, Adrian P. Mancusoc, Brian A. Federici, Henry N. Chapman, Neil Crickmore, Pierre J. Rizkallah, Colin Berry, and Dominik Oberthür. 2024. Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated from natural crystals using MHz-SFX. Proceedings of the National Academy of Sciences 120 (49) e2203241120. https://doi.org/10.1073/pnas.2203241120.

95. Rudd, S.R., Miranda Silva, L., Curtis, H.C., Bigot, Y., Diaz-Mendoza, M., Hice, R., Nizet, V., Park, H.-W., Blaha, G., Federici, B.A., Bideshi, D.K. 2023. The parasporal body of Bacillus thuringiensis subsp. israelensis: A unique phage capsid-associated prokaryotic insecticidal organelle. BIOLOGY, 12(11):1421. https://doi.org/10.3390/biology12111421.

94. Barboza-Corona, J.E., Bideshi, D.K., Park, H.-W., Salcedo-Hernandez, R. 2023. Editorial: Novel Research on metabolites secreted by gram-positive bacteria. Frontiers in Microbiology 14:1237790/ DOI 10.3389/fmicb.2023.1237790.

93. Guillaume Tetreau, Michael R. Sawaya, Elke De Zitter, Elena A. Andreeva, Anne-Sophie Banneville, Natalie A. Schibrowsky, Nicolas Coquelle, Aaron S. Brewster, Marie Luise Grünbein, Gabriela Nass Kovacs, Mark S. Hunter, Marco Kloos, Raymond G. Sierra, Giorgio Schiro, Pei Qiao, Myriam Stricker, Dennis Bideshi, Iris D. Young, Ninon Zala, Sylvain Engilberge, Alexander Gorel, Luca Signor, Jean-Marie Teulon, Mario Hilpert, Lutz Foucar, Johan Bielecki, Richard Bean, Raphael de Wijn, Tokushi Sato, Henry Kirkwood, Romain Letrun, Alexander Batyuk, Irina Snigireva, Daphna Fenel, Robin Schubert, Ethan J. Canfield, Mario M. Alba, Frédéric Laporte, Laurence Després, Maria Bacia, Amandine Roux, Christian Chapelle, François Riobé, Olivier Maury, Wai Li Ling, Sébastien Boutet, Adrian Mancuso, Irina Gutsche, Eric Girard, Thomas R. M. Barends, Jean-Luc Pellequer, Hyun-Woo Park, Arthur D. Laganowsky, Jose Rodriguez, Manfred Burghammer, Robert L. Shoeman, R. Bruce Doak, Martin Weik, Nicholas K. Sauter, Brian Federici, Duilio Cascio, Ilme Schlichting, Jacques-Philippe Colletier. 2022. De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals. Nature Communication 13(1):4376; https://doi.org/10.1038/s41467-022-31746-x

92. Pérez-Rangel, M., Valdez-Vazquez, I., Martínez-Zavala, S.A., Casados-Vázquez, L.E., Bideshi, D.K, Barboza-Corona, J.E. 2022. Evaluation of inhibitory compounds produced by bacteria isolated from a hydrogen-producing bioreactor during the self-fermentation of wheat straw. Journal of Applied Microbiology 133(2):1989-2001. doi: 10.1111/jam.15708.


91. Ortiz Rodríguez, T., Mendoza Acosta, F., Martínez Zavala, S.A., Salcedo Hernández, R., Casados Vázquez, L.E., · Bideshi, D.K., Barboza Corona, J.E. 2022. Thurincin H is a Nonhemolytic Bacteriocin of Bacillus thuringiensis with Potential for Applied Use. Probiotics and Antimicrobial Proteins https://doi.org/10.1007/s12602-022-09952-2.

90. Zaghloul, H.A.H., Hice, R.H., Arensburger, P., Bideshi, D.K., Federici, B.A. 2021. Extended in vivo transcriptomes of two ascoviruses with different tissue tropisms reveal alternative mechanisms for enhancing virus reproduction in hemolymph. Scientific Reports (2021) 11:16402, https:/doi.org/10.1038/s41598-021-95553-y.

89. Asgari, S., Bideshi, D.K., Bigot, Y., Federici, B.A. 2021. Ascoviruses (Ascoviridae, Ascovirus, and Toursvirus). Encyclopedia of Virology. https://doi.org/10.1016/B978-0-12-809633-8.21548-3.

88. Celaya-Herrera, S., Casados-Vazquez, L., Valdez-Vazquez, I., Barona-Gomez, F., Bideshi, D.K., Barboza-Corona, J.E. 2020. A cellulolytic Streptomyces sp. isolated from a highly oligotrophic niche shows potential for hydrolyzing agricultural wastes. BioEnergy Research. https:/doi.org/10.1007/s12155-020-10174-z.

87. Pérez-Zavala, De L., Hernández-Arzaba, J.C., Bideshi, D.K., Barboza-Corona, J.E. 2020. Agave: A natural renewable resource with multiple applications. Journal of the Science of Food and Agriculture. DOI:10.1002/jsfa.10586.

86. Zaghloul, H.A.H., Hice, R., Bideshi, D.K., Arensburger, P., Federici, B.A. 2020. Mitochondrial and innate immune transcriptomes from Spodoptera frugiperda infected with the Spodoptera frugiperda ascovirus. Journal of Virology. https://jvi.asm.org/content/early/2020/02/14/JVI.01985-19

85. Pacheco-Cano, R.D., Salcedo-Hernandez, R., Casados-Vasquez, L.E., Wrobel, K., Bideshi, D.K., Barboza-Corona, E. 2020. Class 1 defensins from broccoli (Brassica oleracea var. italica) seeds and their antimicrobial activity. World Journal of Microbiology and Biotechnology 5, 36(2):30; doi.org/10.1007/s11274-020-2807-6.

84. Hernandez-Saldana, O.F., Barboza-Corona, J.E., Bideshi, D.K., Casados-Vazquez, L.E. 2020. New bacteriocin-like substances produced by Streptomyces species with activities against pathogens. Folia Microbiologica. doi.org./10.1007/s12223-020-00770-z.

83. Martinez-Zavala, S.A., Barboza-Perez, U.E., Hernandez-Guzman, G., Bideshi, D.K., Barboza-Corona, J.E. 2020. Chitinases of Bacillus thuringiensis: Phylogeny, Modular Structure, and Applied Potentials. Frontiers in Microbiology. doi: 10.3389/fmicb.2019.03032.

82. Gonzalez-Ponce, K.S., Casados-Vasques, L.E., Lozano-Sotomayor, P., Bideshi, D.K., Del Rincon-Castro, M.C., Barboza-Corona, J.E. 2019. Expression of ChiA74Δsp and its truncated versions in Bacillus thuringiensis HD1 using a vegetative promoter maintains the integrity and toxicity of native Cry1A toxins. International Journal of Biological Macromolecules 124:80-87. doi.org/10.1016/j.ijbiomac.2018.11.173.

81. Bideshi, D.K., Spears, T., Zaghloul, H.A.H., Tan, Y., Bigot, Y., Federici, B.A. 2018. Ascovirus P64 Homologs: A novel family of large cationic proteins that condense viral genomic DNA for encapsidation. Biology 7, 44; doi:10.3390/biology7030044.

80. Oros-Flores, Z.S,, Casados-Vázquez L.E., Bideshi D.K., Salcedo-Hernández R, Barboza-Corona J,E. 2018. Co-synthesis of kenyacin 404 and heterologous thurincin H enhances the antibacterial activity of Bacillus thuringiensis. Biotechnology Letters. doi: 10.1007/s10529-018-2601-9.

79. Casados-Vasquez, L.E., Bideshi, D.K.,, Barboza-Corona, J.E. 2018. Regulator ThnR and the ThnDE ABC transporter proteins confer autoimmunity to thurincin H in Bacillus thuringiensis. Antonie van Leeuwenhoek https://doi.org/10.1007/s10482-018-1124-7

78. Pacheco-Cano, R.D., Salcedo-Hernández, R., López-Meza, J.E., Bideshi, D.K., Barboza-Corona. J.E. 2018. Antimicrobial activity of broccoli (Brassica oleracea var. italica) cultivar Avenger against pathogenic bacteria, phytopathogenic filamentous fungi, and yeast. Journal of Applied Microbiology, 124:126-135. doi: 10.1111/jam.13629

77. Bideshi, D.K., Park, H.-W., Hice, R.H., Wirth M.C., Federici, B.A. 2017. Highly effective broad spectrum chimeric larvicide that targets vector mosquitoes using a lipophilic protein. Scientific Reports 7: 11282. DOI:10.1038/s41598-017-11717-9.

76. Sakano, Y., Park, H.-W., Bideshi, D. K., Ge, B., Federici, B.A. 2017. Contributions of 5'-UTR and 3'-UTR cis elements to Cyt1Aa synthesis in Bacillus thuringiensis subsp. israelensis. Journal of Invertebrate Pathology 149:66-75. doi.org/10.1016/j.jip.2017.08.002

75. Juárez-Hernández, E.O., Casados-Vázquez, L.E., Bideshi, D.K., Salcedo-Hernández, R., Barboza-Corona, J.E. 2017. Role of the C-terminal and chitin insertion domains on enzymatic activity of endochitinase ChiA74 of Bacillus thuringiensis. International Journal of Biological Macromolecules 102:52-59. DOI: 10.1016/j.ijbiomac.2017.03.191

74. Asgari, S., Bideshi, D. K., Bigot, B., Federici, B. A., Cheng, X.-W. and ICTV Report Consortium. 2017. ICTV Virus Taxonomy Profile: Ascoviridae. Journal of General Virology, 98:4-5. DOI 10.1099/jgv.0.000677.

73. González‑Ponce, K. S., · Casados‑Vázquez, L. E., Salcedo‑Hernández, R., Bideshi, D. K., · del Rincón‑Castro, M.C., Barboza‑Corona, J. E. 2017. Recombinant Bacillus thuringiensis subsp. kurstaki HD73 strain that synthesizes Cry1Ac and chimeric ChiA74Δsp chitinase inclusions. Archive of Microbiology 199:627-633. DOI 10.1007/s00203-017-1339-4

72. Casados-Vázquez LE, Bideshi DK, Barboza-Corona JE. 2016. The thnR gene is a negative transcription regulator of the thurincin H genetic cassette in Bacillus thuringiensis subsp. morrisoni. Archives of Microbiology 199:385-390. doi: 10.1007/s00203-016-1298-1:

71. Jacques-Philippe Colletier, Michael R. Sawaya, Mari Gingery, Jose A. Rodriguez, Duilio Cascio, Aaron S. Brewster, Tara Michels-Clark, Robert H. Hice, Nicolas Coquelle, Sébastien Boutet, Garth J. Williams, Marc Messerschmidt,Daniel P. DePonte, Raymond G. Sierra, Hartawan Laksmono, Jason E. Koglin, Mark S. Hunter, Hyun-Woo Park, Monarin Uervirojnangkoorn, Dennis K. Bideshi, Axel T. Brunger, Brian A. Federici, Nicholas K. Sauter and David S. Eisenberg. 2016. De novo phasing with X-ray laser reveals
mosquito larvicide BinAB structure. Nature 539(7627):43-47. doi:10.1038/nature19825

70. Fiedoruk, K., Daniluk, T., Fiodor, A., Drewicka, E., Buzynska, K., Leszczynska, K., Bideshi, D. K., Swiecicka, I. 2016. MALDI-TOF portrait of emetic and non-emetic Bacillus cereus group members. Electrophoresis. 37(15-16):2235-2237. doi. 10.1002/elps.201500308.

69. de la Fuente-Salcido, N. M., Casados-Vazquezm L. E., Garcia-Perez, A. P., Barboza-Corona, U. E., Bideshi, D .K., Salcedo-Hernandez, R., Garcia-Almendarez, B. E., Barboza-Corona, J. E. 2016. The endochitinase ChiA Btt of Bacillus thuringiensis subsp. tenebrionis DSM-2803 and its potential use to control the phytopathogen Colletotrichum gloeosporioides. Microbiology Open. 2016 May 12.doi: 10.1002/mbo3.372

68. Hernandez-Saldana, O. F., Valencia-Posadas, M., de la Fuente-Salcido, N. M., Bideshi, D. K., Barboza-Corona, J. E. 2016. Bacteriocinogenic bacteria isolated from raw goat milk and goat cheese produced in the center of Mexico. Indian Journal of Microbiology. 56(3):301-308. doi: 10.1007/s12088-016-0587-3.

67. Juárez-Hernández, E.O., Casados-Vázquez, L.E., Del Rincón-Castro, M.C., Salcedo-Hernández, R., Bideshi, D.K., Barboza-Corona, J.E. 2015. Bacillus thuringiensis subsp. israelensis producing endochitinase ChiA74Δsp inclusions and its improved activity against Aedes aegypti. Journal of Applied Microbiology. 119(6):1692-1699. doi: 10.1111/jam.12962.

66. Gutierrez-Chavez, A.J., Martinez-Ortega, E.A., Valencia-Posadas, M., Leon Galvan, M.F., de la Fuente-Salcido, N.M., Bideshi, D.K., Barboza-Corona, J.E. 2015. Potential use of Bacillus thuringiensis bacteriocins to control antibiotic-resistant bacteria associated with mastitis in dairy goats. Folia Microbiologica. 61(1):11-19. doi. 10.1007/s12223-015-0404-0

65. de la Fuente-Salcido, N.M., Castaneda-Ramirez, J.C., Garcia-Almendarez, B.E., Bideshi, D.K., Salcedo-Hernandez, R., Barboza-Corona, J.E. 2015. Isolation and characterization of bacteriocinogenic lactic bacteria from M-Tuba and Tepache, two traditional fermented beverages in Mexico. Food Science and Nutrition 3(5):434-442.

64. Piegu, B., Asgari, A., Bideshi, D.K., Federici, B.A., Bigot, Y. 2015. Evolutionary relationships of iridoviruses and divergence of ascoviruses from invertebrate iridoviruses in the superfamily Megavirales. Molecular Phylogenetics and Evolution 84:44-52; doi: 10.1016/j.ympev.2014.12.013

63. Casados-Vazquez, L.E., Avila-Cabrera, S., Bideshi, D.K., Barboza-Corona, J.E. 2014. Heterologous expression, purification and biochemical characterization of endochitinase ChiA74 from Bacillus thuringiensis. Protein Expression and Purification. S1046-5928(14)00284-8. doi: 10.1016/j.pep.2014.11.015.

62. Piégu, B., Guizard, S., Yeping, T., Cruaud, C., Couloux, A., Bideshi, D.K., Federici, B.A., Bigot Y. 2014. Complete genome sequence of invertebrate iridovirus IIV22A, a variant of IIV22, isolated originally from a blackfly larva. Standard in Genomic Science, 20:940-947.

61. Kaminska, P., Yernazarova, A., Murawska, E., Swiecicki, J. Fiedoruk, K., Bideshi, D.K., Swiecicka, I. 2014. Comparative analysis of quantitative reverse transcription real-time PCR
and commercial enzyme imunoassays for detection of enterotoxigenic Bacillus thuringiensis isolates. FEMS Microbiology Letters, 357:34-39.

60. Pacheco-Cano, R., de la Fuente-Salcido, N., Salcedo-Hernandez, Ruben, Leon-Galvin, M. F., Bideshi, D.K., Hernandez-Guzman, G., Barboza-Corona, J.E. 2014. Characterization, N-terminal sequencing and classification of Tolworthcin 524: A bacteriocin produced by Bacillus thuringiensis subsp. tolworthi. Microbiological Research. S0944-5013(14)00058-5. doi: 10.1016/j.micres.2014.04.005.

59. Piegu, S., Guizard, S., Yeping, T., Cruaud, C., Asgari, S., Bideshi, D.K., Federici, B.A., Bigot, Y. 2014. Genome sequence of a crustacean iridovirus, IIV31, isolated from the pill bug, Armadillidium vulgare. Journal of General Virology, 95:1585-1590.

58. Barboza-Corona, J.E., Luis Delgadillo-Ángeles, J., Castañeda-Ramírez, J.C., Barboza-Pérez, U.E., Casados-Vázquez, L.E., Bideshi, D.K. and del Rincón-Castro, M.C. 2014. Bacillus thuringiensis subsp. kurstaki HD1 as a factory to synthesize alkali-labile ChiA74Δsp chitinase inclusions, Cry crystals and spores for applied use. Microbial Cell Factories, 13:15

57. Piégu, B., Guizard, S., Spears, T., Cruaud, C., Couloux, A., Bideshi, D.K., Federici, B.A. 2014. Complete genome sequence of invertebrate iridovirus IIV30 isolated from the corn earworm, Helicoverpa zea. Journal of Invertebrate Pathology. 116C:43-47..

56. Piégu, B,, Guizard, S., Spears, T., Cruaud, C., Couloux, A., Bideshi, D.K., Federici, B.A., Bigot, Y. 2014. Complete genome sequence of invertebrate iridovirus IIV-25 isolated from a blackfly larva. Archives in Virology, 159:1181-1185..

55. Colson, P., De Lamballerie, S., Yutin, N., Asgari, S., Bigot, Y., Bideshi, D.K., Cheng, X.-W., Federici, B.A., Van Etten, J.L., Koonin, E.V., La Scola, B., Raoult, D. 2013. "Megavirales", a proposed new order for eukaryotic nucleocytoplasmic large DNA viruses. Archives in Virology, 158:2517-21.

54. Piegu, B., Guizard, S., Spears, T., Cruaud, C., Couloux, A., Bideshi, D.K., Federici, B.A., Bigot, Y. 2013. Complete genome sequence of invertebrate iridovirus IIV22 isolated from a blackfly larvae. Journal of General Virology, 94:2112-2116.

53. Bideshi, D.K., Waldrop, G., Fernandez-Luna, M.T., Diaz-Mendoza, M., Wirth, M.C., Johnson, J.J., Park, H.-W., Federici, B.A. 2013. Intermolecular interaction between Cry2Aa and Cyt1Aa and its effect on larvicidal activity against Culex quinquefasciatus. Journal of Microbiology and Biotechnology, 23:1107–1115.

52. Qureshi, N., LeVesque, C.S., Bideshi, D.K., Federici, B.A. 2013. Molecular characterization of a ChaC K+ transport regulator and its transcripts in the glassy-winged sharpshooter, Homaldisca coagulata. Journal of Asia-Pacific Entomology, 16:301-307.

51. Murawska, E., Firdoruk, K., Bideshi, D.K., Swiecicka, I. 2013. Complete genome sequence of Bacillus thuringiensis subsp. thuringiensis strain IS5056, an isolate highly toxic to Trichoplusia ni. Genome Announcement, 1:e0010813.

50. Bigot, Y., Piegu, B., Casteret, S., Gavory, F., Bideshi, D.K., Federici, B.A. 2013. Characteristics of inteins in invertebrate iridoviruses and factors controlling insertion in their viral hosts. Molecular Phylogenetics and Evolution, 67:246-254.

49. Castaneda-Ramirez, J.C., de la Fuente-Salcido, N.M., Salcedo-Hernandez, R., Leon-Galvan, F., Bideshi, D.K., Barboza-Corona, J.E. 2013. High-level synthesis of endochitinase Chi74A in Escherichia coli K12 and its promising potential for use in biotechnology. Folia Microbiologica, 58:455-462.

48. Park, H.-W., Pino, B.C., Kozervanich,-Chong, S., Hafkenscheid, E.A., Oliverio, R.M., Federici, B.A., Bideshi, D.K. 2013. Cyt1Aa from Bacillus thuringiensis subsp. israelensis enhances activity of B. thuringiensis subsp. kurstaki HD-1 against Aedes aegypti but not Culex quinquefasciatus. Journal of Microbiology and Biotechnology, 23:88-91.

47. de la Fuente-Salcido N.M., Barboza-Corona, J.E., Espino Monzon, A.N., Pacheco Cano, R.D., Balagurusamy, N., Bideshi, D.K., Salcedo-Hernandez, R. 2012. Expanding the use of a fluorogenic method to determine activity and mode of action of Bacillus thuringiensis bacteriocins against Gram-positive and Gram-negative bacteria. Scientific World Journal, 2012:503269.

46. Basurto-Cadena M.G., Vazquez-Arista M., Garcia-Jiminez J., Salcedo-Hernandez R., Bideshi D.K., Barboza-Corona J.E. 2012. Isolation of a new Mexican strain of Bacillus subtilis with antifungal and antibacterial activities. Scientific World Journal, 2012:384978.

45. Barboza-Corona J.E., Park H.-W., Bideshi D.K., Federici B.A. 2012. The 60-kDa protein encoded by ORF2 of the cry19A operon in Bacillus thuringiensis subsp. jegathesan functions like a C-terminal crystallization domain. Applied and Environmental Microbiology, 78:2005-2012.

44. Diaz-Mendoza M., Bideshi D.K., Federici B.A. 2012. A 54-kDa protein encoded by pBtoxis is required for parasporal body structural integrity in Bacillus thuringiensis subsp. israelensis. Journal of Bacteriology, 194:1562-1571.

43. Diaz-Mendoza M., Bideshi D.K., Federici B.A. 2012. The 20-kDa chaperone-like protein of Bacillus thuringiensis subsp. israelensis enhances yield, crystal size, and solubility of Cry3A. Letters in Applied Microbiology, 54:88-95.

42. Martínez-Cardeñas J.A., de la Fuente-Salcido N.M., Salcedo N.M., Salcedo-Hernández R., Bideshi D.K. Barboza-Corona JE. 2012. Effects of physical culture parameters on bacteriocin production by Mexican strains of Bacillus thuringiensis after cellular induction. Journal of Industrial Microbiology and Biotechnology, 39:183-189.

41. Swiecicka I., Sztachelska M., Czajkowska M., Bideshi D.K., Federici B.A. 2011. Characterization of Bacillus thuringiensis isolates for soil and small mammals that harbor vip3A gene homologues. Biocontrol Science and Technology, 21:461-472.

40. Park H.-W., Devera J.A., Prins, B.A., Bideshi D.K. 2011. The dual-activity insecticidal protein, Cry2Aa, does not enhance the mosquitocidal actibity of Bacillus thuringiensis subsp. israelensis. Journal of Asia-Pacific Entomology, 14:429-431.

39. Castañeda-Ramírez C., Cortes-Rodríguez V., de la Fuente-Salcido N., Bideshi D.K., del Rincón-Castro M.C., Barboza-Corona J.E. 2011. Isolation of Salmonella spp. From lettuce and evaluation of its susceptibility to novel bacteriocins of Bacillus thuringiensis and antibiotics. Journal of Food Protection, 74:274-278.

38. Federici B.A., Park H.-W., Bideshi D.K. 2010. Overview of the basic biology of Bacillus thuringiensis with emphasis on genetic engineering of bacterial larvicides for mosquito control. The Open Toxinology Journal, 3:154-171.

37. Park, H-W, Bideshi, DK, Federici, B.A. 2010. Properties and applied use if the mosquitocidal bacterium, Bacillus sphaericus. Journal of Asia-Pacific Entomology, 12:159-168.

36. Ortiz-Rodríguez T., de la Fuente-Salcido N., Bideshi D.K., Salcedo-Hernández R., Barboza-Corona J.E. 2010. Generation of chitin-derived oligosaccharides toxic to pathogenic bacteria using ChiA74, an endochitinase native to Bacillus thuringiensis. Letters in Applied Microbiology, 51:184-190.

35. Sciocco A, Bideshi DK, Johnson JJ, Federici BA. 2009. Nucleopolyhedrovirus from the Western Avocado Leafroller, Amorbia cuneana: Isolation and characterization of a potential viral control agent. Biological Control, 49:154-159.

34. Bigot Y., Renault, S., Nicholas J., Moudras C., Demattei M.V., Samain S., Bideshi D.K., Federici B.A. 2009. Symbiotic virus at the evolutionary intersection of three types of large DNA viruses; iridoviruses, ascoviruses, and ichnoviruses. PLoS One, 4(7):e6397

33. Barboza-Corona JE, Ortiz-Rodríguez T, de la Fuente-Salcido N, Bideshi DK, Ibarra JE, Salcedo-Hernández R. 2009. Hyperproduction of chitinase influences crystal toxin synthesis and sporulation of Bacillus thuringiensis. Antonie Van Leeuwenhoek, 96:31-42.

32. Bartoszewicz M, Bideshi DK, Kraszewska A, Modzelewska E, Swiecicka I. 2009. Natural isolates of Bacillus thuringiensis display genetic and psychrotrophic properties characteristic of Bacillus weihenstephanensis. Journal of Applied Microbiology, 106:1976-1975.

31. Federici BA, Bideshi DK, Tan Y, Spears T, Bigot Y. 2009. Ascoviruses: superb manipulators of apoptosis for viral replication and transmission. Current Topics in Microbiology and Immunology, 328:171-96. Review.

30. Barboza-Corona JE, Gutierrez-Acosta OB, Imperial-Cervantes M, Bideshi DK, de la Fuente-Salcido N, Bautista-Justo M, Salcedo-Hernández R. 2009. Generation of antibacterial oligosaccharides derived from chitin using heterologous endochitinase synthesized in Escherichia coli. Journal of Appllied Microbiology, 105:1511-1520.

29. Tan Y, Bideshi DK, Johnson JJ, Bigot Y, Federici BA. 2009. Proteomic analysis of the Spodoptera frugiperda ascovirus 1a virion reveals 21 proteins. Journal of General Virology, 90:359-365.

28. Tan Y, Spears T, Bideshi DK, Johnson JJ, Hice R, Bigot Y, Federici BA. 2009. P64, a novel major virion DNA-binding protein potentially involved in condensing the Spodoptera frugiperda ascovirus 1a genome. Journal of Virology, 83:2708-2714.

27. de la Fuente-Salcido N, Guadalupe Alanís-Guzmán M, Bideshi DK, Salcedo-Hernández R, Bautista-Justo M, Barboza-Corona J.E. 2008. Enhanced synthesis and antimicrobial activities of bacteriocins produced by Mexican strains of Bacillus thuringiensis. Archives in Microbiology, 190:633-640.

26. Swiecicka I, Bideshi DK, Federici BA. 2008. Novel isolate of Bacillus thuringiensis subsp. thuringiensis that produces a quasicuboidal crystal of Cry1Ab21 toxic to larvae of Trichoplusia ni. Applied and Environmental Microbiology, 74:923-930.

25. Barboza-Corona JE, Reyes-Rios DM, Salcedo-Hernández R, Bideshi DK. 2008. Molecular and biochemical characterization of an endochitinase (ChiA-HD73) from Bacillus thuringiensis subsp. kurstaki HD-73. Molecular Biotechnology, 39:29-37.

24. Tang M, Bideshi DK, Park HW, Federici BA. 2008. Iteron-binding ORF157 and FtsZ-like ORF156 proteins encoded by pBtoxis play a role in its replication in Bacillus thuringiensis subsp. israelensis. Journal of Bacteriology, 189:8053-8058.

23. Federici B, Park HW, Bideshi DK, Wirth MC, Johnson JJ, Sakano Y, Tang M. 2007. Developing recombinant bacteria for control of mosquito larvae. Journal of American Mosquito Control Association, 23:164-175.

22. Park HW, Bideshi DK, Federici BA. 2007. The 20-kDa protein of Bacillus thuringiensis subsp. israelensis enhances Bacillus sphaericus 2362 bin toxin synthesis. Current Microbiology, 55:119-124.

21. de la Fuente-Salcido, N., Selcedo-Hernandez, R., Alanis-Guzman, M. G., Bideshi, D. K.,
Barboza-Corona, J. E. 2007. A new rapid fluorogenic method for measuring
bacteriocin activity. Journal of Microbiological Methods, 7:196-199.

20. Casique-Arroyo, G., Bideshi D. K., Salcedo-Hernandez, R., Barboza-Corona, J. E. 2007. Development of a recombinant strain of Bacillus thuringiensis subsp. kurstaki HD-73 that produces the endochitinase ChiA74. Antonie van Leeuwenhoek, 92:1-9.

19. Barboza-Corona J. E, Vazquez-Acosta H., Bideshi D. K., Salcedo-Hernandez R. 2007.
Bacteriocin-like substances produced by Mexican strains of Bacillus thuringiensis.
Archives of Microbiology, 187:117-26.

18. Bideshi, D. K., Demattei, M. V., Rouleux-Bonnin, F., Stasiak, K., Tan, Y., Bigot, S., Bigot,Y., Federici, B. A. 2006. Genomic sequence of Spodoptera frugiperda ascovirus 1a, a enveloped double-stranded DNA insect virus that manipulates apoptosis for viral
reproduction. Journal of Virology, 80: 11791-11805.

17. Tang, M., Bideshi, D. K., Park, H. W., Federici, B. A. 2006. Minireplicon from pBtoxis of
Bacillus thuringiensis subsp. israelensis. Applied and Environmental Microbiology, 72:6948-6954.

16. Bideshi, D. K., Tan, Y., Bigot, Y. and Federici, B. A. (2005). A viral caspase contributes to cellular differentiation that facilitates virion dissemination. Genes and Development, 19:1416-1421.

15. Park, H-W., Bideshi, D. K., Wirth, M. C., Johnson, J. J., Walton, W. E. and Federici, B. A. (2005). Recombinant larvicidal bacteria with markedly improved efficacy against Culex vectors of West Nile Virus. The American Journal of Tropical Medicine and Hygiene, 72:732-738.

14. Park, H-W., Bideshi, D. K. and Federici, B. A. (2005). Synthesis of additional endotoxins in Bacillus thuringiensis subsp. morrisoni PG-14 and Bacillus thuringiensis subsp. jegathesan significantly improves their mosquitocidal efficacy. Journal of Medical Entomology, 42:337-341.

13. Bideshi, D. K., Renault, S., Stasiak, K., Federici, B. A. and Bigot, Y. (2003). Phylogenetic analysis and possible function of bro-like genes, a multigene family widespread among large double-stranded DNA viruses of invertebrates and bacteria. Journal of General Virology, 84:2531-2544.

12. Federici, B. A., Park, H-W, Bideshi, D. K., Wirth, M.C. and Johnson, J.J.. (2003). Recombinant bacateria for mosquito control. The Journal of Experimental Biology, 206:3877-3885. Invited Review.

11. O'Brochta, D. A., Sethuram, N., Wilson, R., Hice, R. H., Pinkerton, A. C., Levesque, C. S., Bideshi, D. K., Jasinskiene, N., Coates, C. J., James, A. A., Lehane, M. J. and Atkinson, P. W. (2003). Gene Vector and transposable element behavior in mosquitoes. The Journal of Experimental Biology, 206:3823-3834. Invited Review.

10. Park, H-W, Bideshi, D. K., and Federici, B. A. (2003). Recombinant strain of Bacillus thuringiensis producing Cyt1A, Cry11B, and the Bacillus sphaericus binary toxin. Applied and Environmental Microbiology, 69:1331-1334.

9. Guimond, N., Bideshi, D. K., Pinkerton, A. C., Atkinson, P. W. and O'Brochta, D. A. (2003). Patterns of Hermes transposition in Drosophila melanogaster. Molecular Genetics and Genomics, 268:779-790.

8. Bideshi D. K., Bigot, Y., Federici, B. A. (2000). Molecular characterization and phylogenetic analysis of the Harrisina brillians granulovirus gene. Archives of Virology, 145:1933-1945.

7. Park, H. W., Bideshi D. K., Federici, B. A. (2000). Molecular genetic manipulation of truncated Cry1C protein synthesis in Bacillus thuringiensis to improve stability and yield. Applied and Environmental Microbiology, 66:4449-4455.

6. Bideshi, D. K. and Federici B. A. (2000). DNA-independent ATPase activity of the Trichoplusia ni granulovirus DNA helicase. Journal of General Virology, 81:1601-1604.

5. Bideshi, D. K. and Federici, B. A. (2000). The Trichoplusia ni granulovirus helicase is unable to support replication of Autographa californica multicapsid nucleopolyhedrovirus in cells and larvae of T. ni. Journal of General Virology, 81:1593-1599.

4. Bideshi, D. K., Anwar, A. T. and Federici, B. A. (1999). A baculovirus anti-apoptosis gene homology of the Trichoplusia ni granulovirus. Virus Genes, 19:95-101.

3. Park, H., Bideshi, D. K., Johnson, J. J. and Federici, B. A. (1999). Differential enhancement of Cry2A versus Cry11A yields in Bacillus thuringiensis by use of the cry3A STAB mRNA sequence. FEMS Microbiology Letters, 181:319-327.

2. Ge, B., Bideshi, D. K., Moar, W. J. and Federici, B. A. (1998). Differential effects of helper proteins encoded by the cry2A and cry11A operons on the formation of Cry2A inclusions in Bacillus thuringiensis. FEMS Microbiology Letters, 165:35-41.

1. Bideshi, D. K., Hice, R. H., Ge, B. and Federici, B. A. (1998). Molecular characterization and expression of the Trichoplusia ni granulovirus helicase gene. Journal of General Virology, 79:1309-1319.

B. EDITORIAL/SPECIAL TOPICS EDITOR

Lopez-Meza, J. E., Ochoa-Zarzosa, A., Barboza-Corona, J. E., and Bideshi, D. K. 2015. Antimicrobial Peptides: Current and Potential Applications in Biomedical Therapies. BioMed Research International, Vol. 2015, Article ID: 367243; http://dx.doi.org/10.1155/2015/367243.

Barboza-Corona, J.E. Bideshi, D.K., Park, H.-W., Salcedo-Hernandez, R. 2018-2019. Novel Research on Metabolites Secreted by Gram-Positive Bacteria. Frontiers in Microbiology. https://www.frontiersin.org/research-topics/7195/novel-research-on-metabolites-secreted-by-gram-positive-bacteria#articles


C. PROCEEDINGS/SYMPOSIA

1. Federici, B.A., H.-W. Park and D.K. Bideshi. 2001. Improving the Efficacy of Bacillus thuringiensis Insecticides: From Molecular Biology to Practical Applications. In: Proceedings of the Centennial Symposium Commemorating Ishiwata's Discovery of Bacillus thuringiensis." (M. Ohba, O. Nakamura, E. Mizuki and T. Akao, editors), pp. 15-20. Kurume, Japan.

2. Federici, B.A., H.-W. Park, D.K. Bideshi, J.J. Johnson and M.C. Wirth. 2001. Synergistic Interactions that Enhance the Pathogenicity of Bacillus thuringiensis. In: "Proceedings of the 4th Pacific Rim Conference on the Biotechnology of Bacillus thuringiensis and its Environmental Impact." Canberra, Australia.


D. BOOK CHAPTERS

1. Bigot, Y., Asgari, S., Bideshi, D.K., Cheng, X.W., Federici, B.A., and Renault S. 2012. Ascoviridae: In Virus Taxonomy: Ninth Report of the International Committee on Taxonomy of Viruses. (A.M.Q. King, M.J. Adams, E. Lefkowitz, E.B. Carstens, Editors). pp. 147-152. Academic Press, Elsevier, San Diego, USA.

2. Bideshi, D.K., Bigot, Y., Federici, B.A., and Spears, T. 2010. Ascoviruses. Insect Virology. (Sassan Asgari and Karyn N. Johnson, Editors). pp. 3-24. Caister Academic Press, Great Britain.

3. Federici, B. A., Park, H-W., Bideshi, D. K. and Ge, B. 2000. Chapter 7.2. "GeneticEngineering of Bacterial Insecticides for Improved Efficacy Against Medically Important Diptera. In: "Entomopathogenic Bacteria: From Laboratory to Field Application". (J. F. Charles, A. Delecluse and C. Niesen-LeRoux, Editors.). pp. 461-484. Kluwer Academic Publishers, Amsterdam.


E. PRESENTATIONS

68. Salem Atallah, Dennis K. Bideshi. 2023. A Newly Developed HIV Vaccine Modeled After SARS-CoV2 mRNA Vaccine: Review of the Incidence of COVID-19 Symptoms in HIV Patients, Social Challenges, and Future Prospects. 15th Annual Natural and Mathematical Sciences Research Symposium, Innovators Auditorium, California Baptist University, 8432 Magnolia Avenue, Riverside, CA 92504; March 25th, 2023.

67. Paola Reyes, Wyatt Grayson, Sarai McCullough, Eugene Chen, Leticia Silva Miranda, Sarah R. Rudd, Dr. Hyun-Woo (Andrew) Park, Dennis K. Bideshi. 2023. Exploration Into the Development of Efficacious Mosquito Larvicides: A. Expression Cyt1Aa-Cry11Aa Chimera in Bacillus thuringiensis subsp. israelensis. 15th Annual Natural and Mathematical Sciences Research Symposium, Innovators Auditorium, California Baptist University, 8432 Magnolia Avenue, Riverside, CA 92504; March 25th, 2023.

66. Nikita Calitz, Elizabeth Ewing, Janelle Ferneyhough, Irais Rodriguez, Leticia Silva Miranda, Sarah R. Rudd, Dr. Hyun-Woo (Andrew) Park, Dennis K. Bideshi. 2023. Exploration Into the Development of Efficacious Mosquito Larvicides: B. Expression Cyt1Aa-Cry11Ba Chimera in Bacillus thuringiensis subsp. israelensis. 15th Annual Natural and Mathematical Sciences Research Symposium, Innovators Auditorium, California Baptist University, 8432 Magnolia Avenue, Riverside, CA 92504; March 25th, 2023.

65. Sarah R. Rudd, Leticia Silva Miranda, Dr. Hyun-Woo (Andrew) Park, Dennis K. Bideshi. 2023. A Practical Approach for Developing a Cyt1Aa-Cry3Aa-Based Degradable Biopesticide that Delays or Prevents Resistance in Natural Coleopteran Pest Populations. 15th Annual Natural and Mathematical Sciences Research Symposium, Innovators Auditorium, California Baptist University, 8432 Magnolia Avenue, Riverside, CA 92504; March 25th, 2023.

64. Colbi Rohr, Alejandro Aguilera, Trinity Nguyen, Joanna Mayorga, Sarah R. Rudd, Dennis K. Bideshi, Hyun-Woo (Andrew) Park. 2023. Molecular Genetic Analysis of the Cry2Aa Operon in Bacillus thuringiensis subsp. kurstaki HD-1. 15th Annual Natural and Mathematical Sciences Research Symposium, Innovators Auditorium, California Baptist University, 8432 Magnolia Avenue, Riverside, CA 92504; March 25th, 2023. 15th Annual Natural and Mathematical Sciences Research Symposium, Innovators Auditorium, California Baptist University, 8432 Magnolia Avenue, Riverside, CA 92504; March 25th, 2023.

63. Gabriella Guevara, Ranaya Barnabas, Sarah R. Rudd, Leticia Silva Miranda, Hyun-Woo (Andrew) Park, Dennis K. Bideshi. 2023. Engineering More Robust Strains of Bacillus thuringiensis subsp. israelensis (Bti) That Express a Highly Toxic Cyt1Aa-BinA Chimera. 15th Annual Natural and Mathematical Sciences Research Symposium, Innovators Auditorium, California Baptist University, 8432 Magnolia Avenue, Riverside, CA 92504; March 25th, 2023.

62. Leticia Silva Miranda, Sarah R. Rudd, Dr. Hyun-Woo (Andrew) Park, Dennis K. Bideshi. 2023. 3-D Modeling of the 20 kDa Chaperone Protein of Bacillus thuringiensis subsp. israelensis Reveals Structural Homology With its Cytolytic (Cyt) Mosquitocidal Toxins. 15th Annual Natural and Mathematical Sciences Research Symposium, Innovators Auditorium, California Baptist University, 8432 Magnolia Avenue, Riverside, CA 92504; March 25th, 2023.

61. Oscar Mena, Sharon Asariah, Piper Hudspeth, Sarah R. Rudd, Hannah Curtis, Michael Alonso, Amy Kirk, Leticia Silva Miranda, Dr. Hyun-Woo (Andrew) Park, Dennis K. Bideshi. 2023. Synchronous Expression of BinA/BinB and a Low Level of Cyt1Aa Results in a Highly Efficacious Mosquito Larvicidal of Bacillus thuringiensis subsp. israelensis. 15th Annual Natural and Mathematical Sciences Research Symposium, Innovators Auditorium, California Baptist University, 8432 Magnolia Avenue, Riverside, CA 92504; March 25th, 2023.

60. Oscar Mena, Angelique Gutierrez, Sharon Asariah, Esmeralda Espino, Hyun-Woo (Andrew) Park, Dennis K. Bideshi. 2022. Construction of an Artificial Operon for Synchronous Expression of Cyt1Aa and the BinA/B Binary Mosquito Larvicidal Toxins. 14th Annual Natural and Mathematical Sciences Research Symposium, March 26th, 2022.

59. Daniella Sternberg, Madison Sonerholm, Nathan Waibel, Hyun-Woo (Andrew) Park, Dennis K. 2022. A Genetic Cassette for Uniform Expression of a Cyt1Aa-BinB Chimera and BinA with Potential for Applied in Vector Mosquito Control Presenter. 14th Annual Natural and Mathematical Sciences Research Symposium, March 26th, 2022.

58. Kacie Dennis, Amy Nicole-Anne Kirk, Samuel Nguyen, Dennis K. Bideshi, Hyun-Woo (Andrew) Park. 2022. Construction of the Plasmid for In Vivo Homologous Recombination in Bacillus thuringiensis . 14th Annual Natural and Mathematical Sciences Research Symposium, March 26th, 2022.

57. Lexi Quartaro, Alex Sarmiento, Dilan Ajtun, Genesis Baltazar, Sarah Hoover, Shalaine Tolentino, Dennis K. Bideshi, Hyun-Woo. 2022. Detection of Enterotoxin Genes of Bacillus cereus on Organic Produce Presenters. 14th Annual Natural and Mathematical Sciences Research Symposium, March 26th, 2022.

56. Peter J. Sells, Garrett R. Petersen, Johnna R. Dreschler, Sarah Renee Rudd, Brian A. Federici, Yves Bigot, Hyun-Woo Park, Dennis K. Bideshi. 2021. Expanding the Utility of Encapsulins In Prokaryotes: A Novel Capsid-Based Entomotoxigenic Microcompartment in Bacillus thuringiensis subsp. israelensis? 13th Annual Natural and Mathematical Sciences Research Symposium; Saturday March 27th, 2021.

55. Kacie Dennis, Emily Ibarra, Amanda Lee, Joseph Kim, Robert Marks, Tuesday Martin, Brian A. Federici, Dennis K. Bideshi, Hyun-Woo (Andrew) Park. 2021. Re-engineering the Bacillus thuringiensis subsp. israelensis Strain producing the Lysinibacillus sphaericus Bin Toxin by in Vivo Homologous Recombination. 13th Annual Natural and Mathematical Sciences Research Symposium; Saturday March 27th, 2021.

54. Yagoda J. Jedrzejczak, Giselle E. Espinosa, Talia M. Basch, Sarah Renee Rudd, Hyun-Woo Park, Dennis K. Bideshi. 2020. Determination of the Medium Lethal Time (LT50) of a Novel Cyt1Aa:BinA Protein Chimera for Applied use in Vector Control. 12th Annual Natural and Mathematical Sciences Research Symposium. March 7th, 2020; Yeager Center, California Baptist University.

53. Joshua Carter, Phillip Ndowu, Daniel Ruiz, Sheldon Borson, Dennis K. Bideshi, Hyun-Woo Park. 2020. Re-engineering Bacillus thuringiensis subsp. israelensis producing Lysinibacillus sphaericus 2362 Bin Using Homologous Recombination. 12th Annual Natural and Mathematical Sciences Research Symposium. March 7th, 2020; Yeager Center, California Baptist University.

52. Federici, B. A., D. K. Bideshi, H.-W. Park, R. H. Hice, W. E. Walton and P. Arensburger. 2020. Recombinant bacteria for mosquito larval control. 3rd Annual Progress & Planning Meeting of the Pacific Southwest Center of Excellence in Vector-Borne Diseases, University of California, Riverside.

51. Park , H.-W., Bideshi, D.K., Federici, B.A. 2019. Improvement of the recombinant Bacillus thuringiensis strain producing the Cyt1A-BinA chimera by combining with Cry11B. 2019 Spring International Conference of the Korean Society for Applied Entomology, Cheongju, Korea; April 25, 2019.

50. Bideshi, D.K. 2019. Ascovirus P64 Homologs: A novel family of large cationic proteins that condense viral genomic DNA for encapsidation. Natural and Mathematical Sciences Research Symposium, California Baptist University, Riverside, California 92504; February 23, 2019.

49. Grossheim, C. M., Thompson, R. I., Hice, H.R., Bigot, Y., Bideshi, D.K., Federici, H.-W., Federici, B.A. 2019. Identification of the putative bipyramidal crystal protein gene from Bacillus thuringiensis subsp. morrisoni PG-14. Natural and Mathematical Sciences Research Symposium, California Baptist University, Riverside, California 92504; February 23, 2019.

48. Fernandez, N., Zuniga, M., Hernandez, K., Bryant, S.E., Park, H.-W., Federici, B.A., Bideshi, D.K. 2019. Genetically engineering microbial factories that produce highly effective combinations of Cry4Aa, Cry4Ba, Cry11Aa, Cyt1Aa, and the novel Cyt1Aa-BinA chimera for applied use in vector mosquito control. 44th Annual West Coast Biological Sciences Undergraduate Research Conference on April 6th, 2019, University of San Diego.

47. Fernandez, N., Zuniga, M., Hernandez, K., Bryant, S.E., Park, H.-W., Federici, B.A., Bideshi, D.K. 2019. Genetically engineering microbial factories that produce highly effective combinations of Cry4Aa, Cry4Ba, Cry11Aa, Cyt1Aa, and the novel Cyt1Aa-BinA chimera for applied use in vector mosquito control. Natural and Mathematical Sciences Research Symposium, California Baptist University, Riverside, California 92504; February 23, 2019.

46. Bideshi, D. K., Park, H.-W., Federici, B.A. 2018. Biology and Pathobiology of Bacillus thuringiensis subsp. israelensis and Lysinibacillus sphaericus, highly efficacious natural mosquito larvicides. Loma Linda University, Department of Earth and Biological Sciences., May 30th, 2018.

45. Bideshi, D.K, Spears, T., Zaghloul, H., Tan, Y., Bigot, Y., and Federici, B.A. 2017. Ascovirus P64 Homologs: A novel family of large cationic proteins that condense viral genomic DNA for encapsidation. 50th Annual Meeting and Golden Jubilee Celebration of the Society for Invertebrate Pathology, August 13-17, 2017; University of California San Diego.

44. Ishii, H., Arai, E., Ince, I.A., Cheng, X.-W., Bideshi, D.K, Inoue, M.N., Federici, B.A., and Nakai, M. 2017. Cry11B Comparative study of fast-killing versus slow-killing SfAV isolates. 50th Annual Meeting and Golden Jubilee Celebration of the Society for Invertebrate Pathology, August 13-17, 2017; University of California San Diego.

43. Park, H.-W., Bideshi, D.K, and Federici, B.A. 2017. Cry11B enhances efficacy significantly to Aedes aegypti when added to a Bacillus thuringiensis strain producing the Cyt1A-BinA chimera. 50th Annual Meeting and Golden Jubilee Celebration of the Society for Invertebrate Pathology, August 13-17, 2017; University of California San Diego.

42. Blackwood, R. Saylor Z., Villasenor, V. 2017. Construction of a recombinant Bacillus thuringiensis strain to synthesize mosquitocidal toxins of Cyt1Aa, BinA and Cry11Ba. 9th Annual Natural and Mathematical Sciences Research Seminar, Innovator’s Auditorium, California Baptist University, February 18, 2017

41. Rudd, S.R,, Bideshi, D.K., Park, H.-W., and Federici, B.A. 2016. Genetic engineering of Bacillus thuringiensis to produce a single mosquitocidal toxin composed of Cyt1Aa, BinA, and Cry11Ba. Eight Annual Natural and Mathematical Sciences Research Seminar, California Baptist University, YCTRA112, February 20, 2016.

40. Curtis, B., Luna, Elizabeth, Bideshi, D. K., Park, H.-W. 2016. Function of BinB protein of Lysinibacillus sphaericus 2362. Eight Annual Natural and Mathematical Sciences Research Seminar, California Baptist University, YCTRA112, February 20, 2016.

39. Searles, S., McCartin, L., Bideshi, D. K., Park, H.-W. 2016. Lysinibacillus sphaericus: Focus on BinA protein and its ability to crystallize in Bacillus thuringiensis. Eight Annual Natural and Mathematical Sciences Research Seminar, California Baptist University, YCTRA112, February 20, 2016.

38. Su, T., M. L. Cheng, M. C. Wirth, J. Thieme, H.-W. Park, D. K. Bideshi and B. A. Federici. 2016. Cross resistance to Lysinibacillus sphaericus in Spinosad-resistant Culex quinquefasciatus is overcome by a Cyt1A-BinA recombinant of Bacillus thuringiensis. 82nd Annual Meeting of the American Mosquito Control Association. Savannah, Georgia.

37. Hiroto Ishi, Ikbal Agah Inche, Xiao-Wen Cheng, Dennis Bideshi, Maki N. Inoue, Yasuhisa Kunimi, Brian Federici, Madoka Nakai. 2016. Comparison of genome replication rates of fast-killing
versus slow-killing SfAV isolates. The International Congress on Invertebrate Pathology and Microbial Control and the 49th Annual Meeting of the Society for Invertebrate Pathology, Vinci Center,Tours, Liore Valley, France, July24-28, 2016.

36. Hyun-Woo Park, Dennis Bideshi, Brian Federici. 2016. A binB knockout in Lysinibacillus sphaericus demonstrates BinA can form a crystal without BinB in Bacillus thuringiensis. The International Congress on Invertebrate Pathology and Microbial Control and the 49th Annual Meeting of the Society for Invertebrate Pathology, Vinci Center,Tours, Liore Valley, France, July24-28, 2016.

35. Jacques-Philippe Colletier, Michael Sawaya, Jose Rodriguez, DuilioCascio, Dennis Bideshi, Robert Hice, Brian Federici, David
Eisenberg. 2016. Lysinibacillus sphaericus Binary toxin structure revealed in situ by de novo phasing with an X-ray free-electron laser: Insights into the larvicidal biology of BinA and BinB. The International Congress on Invertebrate Pathology and Microbial Control and the 49th Annual Meeting of the Society for Invertebrate Pathology, Vinci Center,Tours, Liore Valley, France, July24-28, 2016.

34. Rawley, J. M., A. N. Navarrete, N. R. Bell, E. J. Kettering, D. K. Bideshi and H.-W. Park. 2015. Transformation of Bacillus megaterium for producing insecticidal proteins. 4th Asia-Pacific Congress of Sericulture and Insect Biotechnology. Busan, Korea.
33. Bideshi, D.K., Park, H.-W., Hice, R.H., Wirth, M.C., Federici, B.A. 2015. Cyt1Aa-BinA chimera highly toxic to anopheline, aedine, and culicine larvae including those resistant to Lysinibacillus sphaericus. International Congress on Invertebrate Pathology and Microbial Control, and the 48th Annual Meeting of the Society for Invertebrate Pathology, University of British Columbia, Vancouver, British Columbia, Canada. August 9-13, 2015.

32. Eiko Arai; Shiori Sagawa; Yasumasa Saito; Xiao-Wen Cheng; Dennis Bideshi; Maki Inoue; Yasuhisa Kunimi; Brian Federici; Madoka Nakai. 2014. Characterization of an atypical fast-killing ascovirus: Spodoptera frigiperda ascovirus 1d (SfAV-1d). 2014 International Congress on Invertebrate Pathology and Microbial Control & 47th Annual Meeting of the Society for Invertebrate Pathology;August 3rd to 7th, 2014 at the Johannes Gutenberg University in Mainz, Germany.

31. Sakano, Y., Park, H.-W., Ge, B., Bideshi, D.K., Federici, B.A. 2013. Characterization of a third promoter of the cyt1Aa gene in Bacillus thuringiensis subsp. israelensis. The 46th Annual Meeting of the Society for Invertebrate Pathology; 2013 International Congress on Invertebrate Pathology and Microbial Control. Sheraton Hotel at Station Square, Pittsburg, PA, USA. August 11-15th, 2013.

30. Mercedes Diaz-Mendoza, Dennis K. Bideshi, Brian A. Federici. 2012. The 54-kDa protein of Bacillus thuringiensis subsp. israelensis required for parasporal body stability binds to individual endotoxin inclusions during their development. The 45th Annual Meeting of the Society for Invertebrate Pathology; 2012 International Congress on Invertebrate Pathology and Microbial Control. Centro de Convenciones de la UCA, Puerto Madero, Buenos Aires, Argentina. August 5-9th, 2012.

29. Park, H.-W., J. A. Devera, B. A. Prins, R. Maynard and D. K. Bideshi. 2012. The dual-activity insecticidal protein, Cry2Aa, does not enhance the mosquitocidal activity of Bacillus thuringiensis subsp. israelensis. 67th Annual Meeting of the American Scientific Affiliation. San Diego, California. July 20-23.

28. B. A. Federici, Margaret C. Wirth, Jeffrey J. Johnson, Hyun-Woo Park, Dennis K. Bideshi, William E. Walton. CytlA of Bacillus thuringiensis restores Bacillus sphaericus Bin toxicity via large microvillar lesions, not cation channels, in Bin-Resistant larvae of Culex quinquefasciatus. 44th Annual Meeting of the Society for Invertebrate Pathology, St. Mary’s University, Halifax, Nova Scotia, Canada. August 7-11th , 2011.

27. J. Eleazar Barboza-Corona, Hyun-Woo Park, Dennis K. Bideshi, Brian A. Federici. The 60-kDa protein encoded by orf2 in the cry19A operon of Bacillus thuringiensis subsp. jegathesan functions like a C-terminus of the 135-kDa Class Cry proteins. 44th Annual Meeting of the Society for Invertebrate Pathology, St. Mary’s University, Halifax, Nova Scotia, Canada. August 7-11th , 2011.

26. I. Swiecicka, M. Bartoszewicz, D.K. Bideshi. Psycrotolerance and genetic characteristics of natural Bacillus thuringiensis isolates from Northeastern Poland. HE International Conference on Bacillus anthracis, B. cereus, and B. thuringienisis. Bruges, Oud Sint-Jan, Belgium. August 7-11, 2011.

25. Bideshi, D. K., G. Waldrop, M. C. Wirth, J. J. Johnson, M. Diaz-Mendoza, H.-W. Park and B. A. Federici. 2010. Cyt1Aa Synergizes the Larvicidal Activity of Cry2Aa against Culex quinquefasciatus through direct intermolecular interaction. 43th Annual Meeting of the Society for Invertebrate Pathology, 10th International Colloquium on Invertebrate Pathology and Microbial Control, and The Final Meeting of COST862: Bacterial Toxins for Insect Control. Trabzon, Turkey.

24. Swiecicka, I., Bideshi, D. K., Czajkowska, M., and Kotowicz, S. (2008) Characterization of environmental isolates of Bacillus thuringiensis from Notheastern Poland harbouring vip3A gene homologues. 41st. Annual Meeting of the Society for Invertebrate Pathology and 9th International Conference on Bacillus thuringiensis, University of Warwick, United Kingdom, August 3-7.

23. Tang, M., Bideshi, D.K., Park, H.-W., and Federici, B.A.. (2007). Interactions between ORF157, ORF156 and the iteron in replication of pBtoxis of Bacillus thuringiensis subsp. israelensis. 40th Annual Meeting of the Society for Invertebrate Pathology and 1st International forum on Entomopathogenic Nematodes and Symbiotic Bacteria, Quebec City - Universite Laval, Quebec, Canada; August 12-16

22. Tan, Y., Bideshi, D. K., Bigot, Y., and Federici, B. A. (2007). Identification of virion proteins of Spodoptera frigiperda ascovirus by mass spectroscopy. 40th Annual Meeting of the Society for Invertebrate Pathology and 1st International forum on Entomopathogenic Nematodes and Symbiotic Bacteria, Quebec City -Universite Laval, Quebec, Canada; August 12-16

21. Swiecicka, I., Bideshi, D. K., and Federici, B. A. 2007. A novel Bacillus thuringiensis isolate that produces cuboidal crystals and is highly toxic to larvae of Trichoplusia ni. 40th Annual Meeting of the Society for Invertebrate Pathology and 1st International forum on Entomopathogenic Nematodes and Symbiotic Bacteria, Quebec City -Universite Laval,Quebec, Canada; August 12-16

20. Tang, M., Bideshi, D. K., Park, H.-W., and Federici, B. A. 2006 A mini-replicon from pBtoxis of Bacillus thuringiensis subsp. israelensis. 39th Annual Meeting of the Society for Invertebrate Pathology, IXth International Colloquium on Invertebrate Pathology and Microbial Control, and XIIIth International Conference on Bacillus thuringiensis. Wuhan, China. August 27th to September 1st.

19. Federici, B. A., Bideshi, D. K., Park, H.-W., Johnson, J. J., Tang,M., Wirth, M., Sakano, Y. 2006. Improved genetically engineered bacteria for controlling mosquito larvae. 9th International Colloquium on Invertebrate Pathology and Microbial Control; 39th Annual meeting of the SIP 8th International conferences on Bacillus thuringiensis; August 27th to September 1st, 2006.

18. Bideshi, D. K., Deem, R., Carr. M. (2004) Stem Cell Research…Is it right for you?
Science Consortium of California Christian Universities: Hosted by California Baptist University,

17. Park, H-W., Bideshi, D. K. and Federici, B. A. (2004) The 20-kDa protein of Bacillus thuringiensis subsp. israelensis enhances B. sphaericus 2362 Bin toxin production. 37th Annual Meeting of the Society for Invertebrate Pathology, August 1-6, Helsinki, Finland.

16. Federici, B. A., Park, H-W., Bideshi, D. K., Sakano, Y. and Wirth, M. C. (2004) From basic research to field application with genetically engineered bacterial insecticides. 37th Annual Meetin of the Society for Invertebrate Pathology, August 1-6, Helsinki, Finland.

15. Tan, Y., Tan, F., Bideshi, D. K. and Federici, B. A. (2004) A new Ascovirus (SeAV6A) isolated from Spodoptera exigua larvae in California. 37th Annual Meetin of the Society for Invertebrate Pathology, August 1-6, Helsinki, Finland.

14. Park, H. W., B. A. Federici, D. K. Bideshi, M. C. Wirth and W. E. Walton. (2003) Recent progress on recombinant larvicidal bacteria for mosquito control. 71st Annual Conference of the Mosquito and Vector Control Association of California. Palm Springs, California.

13. Federici, B. A., M. C. Wirth, J. J. Johnson, H. W. Park, D. K. Bideshi and W. E. Walton. (2003) Cyt1A synergizes toxicity of Bs Bin by enhancing its insertion through the mosquito midgut microvillar membrane. 36th Annual Meeting of the Society for Invertebrate Pathology. Burlington, Vermont.

12. Federici, B. A., H. W. Park, D. K. Bideshi, J. J. Johnson, M. C. Wirth and W. E. Walton. (2002) Genetically engineered bacterial larvicides with markedly improved properties for mosquito control. National Conference of the Mosquito Control Association of Australia. Gold Coast, Australia.

11. Federici, B. A., H. W. Park, D. K. Bideshi, J. J. Johnson, M. C. Wirth and W. E. Walton. (2002) New recombinant bacteria for mosquito control. 70th Annual Conference of the Mosquito and Vector Control Association of California. Fish Camp, California.

10. Park, H. W., D. K. Bideshi and B. A. Federici. (2002) Addition of the Bacillus sphaericus binary toxin to Bacillus thuringiensis subsp. morrisoni (PG-14) and Bacillus thuringiensis subsp. jegathesan markedly improves their toxicity. VIIIth International Colloquium on Invertebrate Pathology and Microbial Control, 35th Annual Meeting of the Society for Invertebrate Pathology and VIth International Conference on Bacillus thuringiensis. Fos do Iguassu, Brazil.

9. Federici, B. A., D. K. Bideshi, H. W. Park, M. C. Wirth, W. E. Walton and J. J. Johnson. (2001) Genetically engineered bacteria containing Bti and Bs proteins for improved control of nuisance and vector mosquito larvae. 69th Annual Conference of the Mosquito and Vector Control Association of California. Napa, California.

8. Park, H. W., D. K. Bideshi and B. A. Federici. (2001) Construction and characterization of a Bacillus thuringiensis strain producing Cry11B, Cyt1A and Bacillus sphaericus 2362 binary toxin. 34th Annual Meeting of the Society for Invertebrate Pathology. Noordwijkerhout, The Netherlands.

7. Federici, B. A., D. K. Bideshi, H. W. Park, M. C. Wirth, W. E. Walton and J. J. Johnson. (2001) Markedly improved recombinant Bacillus thuringiensis subsp. israelensis that synthesizes a high level of the Bacillus sphaericus binary toxin. 34th Annual Meeting of the Society for Invertebrate Pathology. Noordwijkerhout, The Netherlands.

6. Federici, B. A., H. W. Park, D. K. Bideshi, J. J. Johnson, M. C. Wirth and W. E. Walton. (2001) New recombinant bacterial larvicides for mosquito control. 2001 Entomological Society of America Annual Meeting. San Diego, California.

5. Federici, B. A., M. C. Wirth, D. K. Bideshi, H. W. Park and W. E. Walton. (2000) Role of Cyt1A in managing resistance to mosquitocidal proteins of Bacillus thuringiensis and Bacillus sphaericus. 33rd Annual Meeting of the Society for Invertebrate Pathology and Vth International Conference on Bacillus thuringiensis. Guanajuato, Mexico.

4. Federici, B. A., D. K. Bideshi, H. W. Park, M. C. Wirth, W. E. Walton and J. J. Johnson. (2000) Markedly improved bacterial insecticides for vectors by combining Bti and Bs proteins. 33rd Annual Meeting of the Society for Invertebrate Pathology and Vth International Conference on Bacillus thuringiensis. Guanajuato, Mexico.

3. Bideshi, D. K. and Federici, B. A. (1999) Functional analysis of the putative DNA helicase, P137, of the Trichoplusia ni granulovirus. XXXII Meeting of the Society for Invertebrate Pathology, August 22-27, University of California Irvine.

2. Bideshi, D. K., Bigot, Y., Stasiak, K. and Federici, B. A. (1999) Phylogeny of Baculoviruses based on 5'-untranslated sequences of occlusion protein genes. XXXII Meeting of the Society for Invertebrate Pathology, August 22-27, University of California Irvine.

1. Bideshi, D. K., Bigot, Y. and Federici, B. A. (1999) Molecular characterization and phylogenetic analysis of the Harrisina brillians granulosis virus granulin gene. Meeting of the Society for Invertebrate Pathology, August 22-27, University of California Irvine.

Grace Baptist Church
Corona, California

Editorial Committee
Current Trends on Biotechnology and Microbiology (2021- )

Editorial Board
Madridge Journal of Clinical Research (2017- )

Editorial Board
Journal of Biotechnology and Biomedicine (2019- )

Editorial Board - Academic Editor
Toxins (2019- )

Review/Guest Associate Editor
Frontiers in Microbiology –Microbiotechnology, Ecotoxicology and Bioremediation Section (2019- ).

Editorial Board, Microbiology Section:
Dataset Papers in Science (2012 - July 2017)

Editorial Board, Microbiology Section:
Advances in Biology (2014 - July 2017)


Grace Christian Academy
School Board Member (2014-2016)


American Society for Clinical Pathologists (ASCP)

Society for Invertebrate Pathology (SIP)

Member of Study Group: Ascoviridae Section
International Committee on the Taxonomy of Viruses (ICTV)

"The kingdom of heaven is like a treasure hidden in the field, which a man found and hid again; and from joy over it he goes and sells all that he has and buys that field."

- Matthew 13:44, NASB


"When I stand before God at the end of my life, I would hope that I would not have a single bit of talent left and could say, 'I used everything you gave me.'"
(Erma Bombeck, American Writer)