Faculty Directory

profile

profile

Nathanael Heyman, Ph.D.

Assissant Professor of Biology

Office Phone: (951)552-8533
E-mail: nheyman@calbaptist.edu
Office Location: Mission Hall, 102
Office Hours: M,W,F 11:00-1:00T, TH 11:00-12:00

Degree Major Emphasis Institution Year
Ph.D. Physiological Sciences University of Arizona School of Medicine 2007
B.S. Biology Lee University 1997

Courses Taught

BIO 153 (Anatomy and Physiology I); BIO 163 (Anatomy and Physiology II); BIO 489 (Immunology) ENV 390 (Environmental Stewardship)

+

Academic Areas & Scholarly Interests

Ion channel electrophysiology; Biophysics of Ion Channels; Cardiovascular Physiology; Pulmonary Physiology; Uterine excitability related to pre-mature birth; Exercise Physiology

+

Teaching Experience

1997-1999 High School science teacher (Kingsburg High School, Kingsburg, CA); 1999-2000 Middle School and High School science teacher (Rancho Capistrano Christian School, San Juan Capistrano, CA); 2001-2002 Middle School Science Teacher (Grace Yokley Middle School, Ontario, CA); (2003-2007) Teaching Assistant for Human Physiology for undergraduates and Electrocardiography for medical students (University of Arizona School of Medicine); (2008-2012) Lecturer in "Molecular Mechanisms of Excitability" for graduate students (University of Nevada School of Medicine)

+

Research, Presentations, & Publications

Peer Reviewed Publications;
1. Ek-Vitorin JF, King TJ, Heyman NS, Lampe PD, Burt JM. Selectivity of connexin 43 channels is regulated through protein kinase C-dependent phosphorylation. Circ Res. 2006 Jun 23;98(12):1498-505;

2. Heyman NS, Burt JM. Hindered diffusion through an aqueous pore describes invariant dye selectivity of Cx43 junctions. Biophys J. 2008 Feb 1;94(3):840-54;

3. Heyman NS, Kurjiaka DT, Ek-Vitorin JF, Burt JM. Regulation of gap junctional charge selectivity in Connexin 40 and Connexin 43 co-expressing cells. Am J Physiol Heart Circ Physiol. 2009 Jul;297(1):H450-9;

4. Xiong D, Heyman NS, Airey J, Zhang M, Singer CA, Rawat S, Ye L, Evans R, Burkin DJ, Tian H, McCloskey DT, Valencik M, Britton FC, Duan D, Hume JR. Cardiac Specific, Inducible ClC-3 Gene Deletion Eliminates Native Volume-Sensitive Chloride Channels and Produces Myocardial Hypertrophy in Adult Mice. J Mol Cell Cardiol. 2009 Jul 15;

5. Buxton IL, Heyman N, Wu YY, Barnett S, Ulrich C. A role of stretch-activated potassium currents in the regulation of uterine smooth muscle contraction. Acta Pharmacol Sin 2011 Jun 3;32(6):758-64;

6. Heyman NS, Cowles CL, Barnett SD, Wu YY, Cullison C, Singer CA, Leblanc N, Buxton IL. TREK-1 Currents in Smooth Muscle Cells from Pregnant Human Myometrium. Am J Physiol Cell Physiol. 2013 Jun 26;

7. Yi-Ying Wu, Chad L. Cowles, Scott D. Barnett, Michael T. Lee, Nathanael S. Heyman, Iain L. O. Buxton. Variants of the Stretch-Activated 2-Pore Potassium Channel Trek-1 Regulate Channel Activity (manuscript under review: Am J Physiol Cell Physiol);

Published Abstracts;
1. Heyman NS, Ek-Vitorin JF, Burt JM. A novel method for determination and measurement of gap junction mediated intercellular communication. Cell Commun Adhes. 2005 May-Jun;12(3-4):86-216;

2. Heyman NS, Burt JM. Independent regulation of electrical and chemical communication via Cx43 gap junctions. Cell Commun Adhes. 2007 Nov-Dec;14(6);

3. Dazhi Xiong, Nathanael Heyman, Judith Airey, Linda Ye, Cherie Singer, Shanti Rawat, Mi Zhang, Rebecca Evans, Dean Burkin, Fiona Britton, Dayue Duan, and Joseph Hume. Heart-Specific Inducible Inactivation of ClC-3 Gene Eliminates Native Volume-Sensitive Outwardly Rectifying Anion Currents (VSOACs) and Results in Cardiac Hypertrophy and Compromised Heart Function. FASEB J. 2009 23:624.6;

4. Nathanael S Heyman, Scott Barnett, Yi-Ying Wu, Cherie Singer, Normand Leblanc, Joseph Hume, and Iain L. O. Buxton. TREK-1 Currents in Smooth Muscle Cells from Pregnant Human Myometrium. FASEB J March 17, 2011 25:1115.20;

Presentations at National or International Scientific Meetings;
1. A novel method for determination and measurement of gap junction mediated intercellular communication; International Gap Junction Meeting; Whistler, British Columbia; 2005. Poster presentation;

2. Are dye and electrical coupling properties of Cx43 comprised gap junctions independently regulated?; American Society for Cell Biology Meeting; San Diego, CA; 2006. Poster and platform presentations;

3. Independent regulation of electrical and chemical communication via Cx43 gap junctions; International Gap Junction Meeting; Helsingor, Denmark; 2007. Platform presentation;

4. Heart-Specific Inducible Inactivation of ClC-3 Gene Eliminates Native Volume-Sensitive Outwardly Rectifying Anion Currents (VSOACs) and Results in Cardiac Hypertrophy and Compromised Heart Function. Experimental Biology Meeting; New Orleans, LA; 2009; Poster presentation;

5. Cardioprotective role for the ClC-3 chloride channel in the mdx mouse model of Duchenne muscular dystrophy. Biophysical Society Meeting; San Francisco, CA; 2010. Poster presentation;

6. TREK-1 Currents in Smooth Muscle Cells from Pregnant Human Myometrium. Experimental Biology Meeting; Washington DC; 2011; Poster presentation;

7. Characterization of Human Myometrial TREK-1 Potassium Channel Currents. Society for Gynecologic investigation; San Diego, CA; 2012; Poster Presentation;

+

Church Membership & Activities

Calvary Chapel Running Springs

+

Interests & Hobbies

I have a lovely wife Tracey, a recently born little girl Natania, and 3 wonderful dogs (Sierra, Tioga, and Glow). I enjoy running, cycling, rock climbing, camping, backpacking, soccer, fly fishing, hunting, and generally enjoying the beauty of God's creation!

+

Personal Philosophy

Colossians 3:23a Whatever you do, work at it with all your heart, as working for the Lord...

+